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Name: saabsaab
Status: N/A
Age: N/A
Location: N/A
Country: N/A
Date: Around 1993


Question:
I am interested in collecting information on Parkinson's Disease. Can you help me?



Replies:
Some possible sources include a neuroscience reference, a neurology text, a neurologist, neuroanatomy references. Basically Parkinson's disease is a movement disorder. It gets more and more difficult to move. One of the primary brain lesions associated with this disease is a shrinkage of an area in the brain stem called the substantia nigra. This is thought to be associated with the neurotransmitter dopamine and there seems to decreased production of the dopamine in this area. Some medications do seem to help including a dopamine replacement medicine called Sinemet. There are some new medicines coming out that may also help. Another exciting area is trying to get new dopamine cells to grow in the substantia nigra area, one way is to insert a needle into the area and inject immature nerve cells into the area and hope they will grow up to be mature dopamine producers, so far it is still considered somewhat experimental. The disease is thought to be caused by progressive cell loss. Some cases have been caused by people who synthesized drugs to abuse and they made a mistake and a bunch of young people took the drug and ended up with the disease. The silver lining of this is that this drug also will do the same thing in rats, so now there is an animal model for Parkinson's.

psych



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