Location: Outside U.S.
Date: Summer 2010
How does a ti plasmid work?
The ti plasmid (tumor-inducing) is associated with
the soil bacterium species Agrobacterium tumefaciens.
It has typical bacterial plasmid features that allow
for replication of the plasmid and expression of genes
with bacterial regulatory sequences. It also has
regions that can be mobilized from the bacterium
when it infects a wound site on a plant. The DNA
called T-DNA is transferred to a plant cell where
it is integrated into the plant genome and encodes
genes that are expressed in the plant and cause the
plant cell to alter its developmental program.