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Name: Matt
Status: Educator
Grade:  Other
Location: CA
Country: United States
Date: Summer 2010
Question:
What makes the cell membrane less permeable as fatigue sets in?


Replies:
Matt,

There are publications that mention the function of levorin which induces permeable channels for free radicals to flow through cell membranes. Levorin also decreases surface tensions of aqueous solutions which aids in increasing cell efficiencies and blood flow during muscle activity. In the case of extensive exercise, there seems to be an increase of free radicals by lipid peroxidation that overwhelm cellular antioxidant defenses, resulting in fatigue and lower physical efficiency. In short, it's an increase of free radicals by lipid peroxidation that hinder levorin from inducing permeable channels through the cell membrane.

"An aromatic heptaene antibiotic levorin and its derivatives in muscle activity" [Kurbanov OG, Kasumov KhM.]

"Production, detection, and adaptive responses to free radicals in exercise." [Sachdev S, Davies KJ.]

Alex Viray


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