Country: United States
Date: February 2007
What exactly are non-allelic genes and how do they
influence other allelic genes?
Non-allelic genes are genes located at different loci on the same
chromosome or on different chromosomes altogether. For example, the gene for
albinism is not an allele of any other gene affecting eye color but affects
eye color by preventing the synthesis of melanin which is deposited in the
iris and determines the color of the eye. This phenomenon whereby a
non-allelic gene masks the expression of another non-allelic gene is known
as epistasis. For more examples, look up epistasis in a genetics text book
or at Wikipedia.com.
Ron Baker, Ph.D.
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Update: June 2012