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Name: Daulat
Status: Other
Grade:  Other
Location: N/A
Country: N/A
Date: January 2007
Question:
What do we mean by coding DNA sequence (CDS)?


Replies:
When DNA sequences are loaded into GenBank, they sometimes contain promoter and regulatory DNA, the 5' cap, untranslated region after the stop codon, or are just whole chunks of DNA from a chromosome for instance. CDS stands for just the sequence that codes for something, either a whole gene or partial gene. It should begin with ATG, and if the protein translation is included in the file, it should begin with M for methionine.

vanhoeck


A coding DNA sequence is simply a DNA sequence that codes for a protein's amino acid sequence. Non-coding sequences refer to DNA sequences that do not code for an amino acid sequence. Examples of non-coding sequences are introns, repetitive sequences (useful in paternity testing) and sequences between genes.Non-coding sequences are sometimes referred to as "junk" DNA.

Ron Baker, Ph.D.


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