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Name: Helen
Status: Student
Grade:  N/A
Location: N/A
Country: United States
Date: March 2005


Question:
What are human homeodomains?



Replies:
The prefix homeo- means the same and domain means region or area. Homeodomains are regions in regulatory proteins found in all species that are made up of the same sequence of 60 amino acids. They are referred to as regulatory proteins because they bind to DNA to either inhibit or promote expression (transcription) of the target gene. This 60 amino acid domain is obviously extremely important since this sequence has remained virtually unchanged over hundreds of millions of years of evolution (from fruit flies to humans). For more information go to Google and search homeodomains.

Ron Baker, Ph.D.



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