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Name: Dr. Philip
Status: Educator
Age: Old
Location: N/A
Country: N/A
Date: September 2004


Question:
Is it possible today to make classical Turner syndrome patients (45, X) fertile by ovary transplants (ovaries with 46, XX karyotypes)?

This question is prompted by the fact that some mosaic patients are fertile if at least one ovary is 46, XX.



Replies:
Dear Dr. Snider:

I had no idea that anything like this was @ all feasible, but I ran across this story today reporting on a Belgian woman who recently gave birth after "a pioneering ovarian tissue transplant", which sounds as though it might be a possibility in the situation that you describe, as well:

http://story.news.yahoo.com/news?tmpl=story&cid=534&e=2&u=/ap/20040924/ap_on_he_me/ovary_baby

Jeff Buzby, Ph.D.
CHOC Research Institute



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