Question:
When I was doing my clinical
training in 1976, I recall reading an article about a person of
Polish descent having both AB antigens on only one allele.Do you
have any knowledge of this case?r
Replies:
I haven't heard of this particular case, but it sounds like a case of
unequal crossing-over during meiosis whereby one chromatid ends up with a
duplication of this chromosome locus (thus carrying both alleles) and the
other chromatid with a deletion of this locus.
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