Department of Energy Argonne National Laboratory Office of Science NEWTON's Homepage NEWTON's Homepage
NEWTON, Ask A Scientist!
NEWTON Home Page NEWTON Teachers Visit Our Archives Ask A Question How To Ask A Question Question of the Week Our Expert Scientists Volunteer at NEWTON! Frequently Asked Questions Referencing NEWTON About NEWTON About Ask A Scientist Education At Argonne Clones From Original Cell
Name: Emily B.
Status: Student
Age: 17
Location: N/A
Country: N/A
Date: December 2002


Question:
If the nucleus is extracted from an adult animal cell and placed into an enucleated egg, how would it be possible to distinguish the cloned individual from the original?



Replies:
It might be easy and might be difficult. For one, the new individual would be a different age than the donor. Also, there are some environmental factors that work on phenotype-think of genetic twins-they are not so identical that you cannot tell them apart. Also, if the clone is a female, there are some phenotypes that the result of X-inactivation.

For instance, last year a cat was cloned-they called it CC for copycat. But the clone did not look like her donor because the donor was a calico cat. Calico pattern is formed by random inactivation of one X chromosome or the other after the 32 cell of development in the embryo. So even though the kitty is genetically identical to the DNA donor, she does not look like her.

vanhoeck



Click here to return to the Molecular Biology Archives

NEWTON is an electronic community for Science, Math, and Computer Science K-12 Educators, sponsored and operated by Argonne National Laboratory's Educational Programs, Andrew Skipor, Ph.D., Head of Educational Programs.

For assistance with NEWTON contact a System Operator (help@newton.dep.anl.gov), or at Argonne's Educational Programs

NEWTON AND ASK A SCIENTIST
Educational Programs
Building 360
9700 S. Cass Ave.
Argonne, Illinois
60439-4845, USA
Update: June 2012
Weclome To Newton

Argonne National Laboratory