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Name: Meghan Lauren S.
Status: Student
Age: 15
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Question:
Can a disorder be autosmal dominant and multifactorial?



Replies:
Multifactorial implies more than one pair of genetic alleles (alleles meaning different versions of one gene...like a flower which has a gene for color being either white or pink). One could have a syndrome where there is a dominant allele involved and other genes playing roles also. In fact many complex diseases...syndromes...are probably of this nature such as certain forms of arthritis, heart disease, diabetes etc.

Peter Faletra Ph.D.
Office of Science
Department of Energy



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