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Name: Stephanie B.
Status: Student
Age: 19
Location: N/A
Country: N/A
Date: N/A 


Question:
I have a research paper on Teratogens, the one I have chosen is Aspirin. I haven't had any luck finding specific details on Aspirin as a teratogen so if you have any information that would be useful then I would really appreciate it!



Replies:
As far as I am aware, aspirin is not considered a teratogen. Its main side-effect is inhibition of blood clotting, which can be either bad or good depending on what other medical conditions you have. It is a risk factor for contracting Reye's syndrome (a particularly nasty complication of chicken pox, I think). I've never heard that it causes birth defects, though.

Richard E. Barrans Jr., Ph.D.
Assistant Director
PG Research Foundation, Darien, Illinois


I am not sure aspirin IS a teratogen, but you can find out quickly by doing a web search on the term "aspirin teratogen" on www.google.com

Vince Calder


Hi Stephani,

Interesting subject! I did not know that aspirin was thought to be teratogenic. If you go to PubMed online (http://www.ncbi.nlm.nih.gov) you can search the scientific literature for any subject related to biomedical issues. They provide the abstracts of most publications. I did a search for 'aspirin, teratogen' and found a few interesting articles on animal models in which the teratogenicity of aspirin (acetyl salicylic acid) was determined. You can check for yourself. Another great site is TERIS, a database on teratogenic agents which has a special on aspirin. See

http://depts.washington.edu/~terisweb/teris/

Trudy Wassenaar



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