Department of Energy Argonne National Laboratory Office of Science NEWTON's Homepage NEWTON's Homepage
NEWTON, Ask A Scientist!
NEWTON Home Page NEWTON Teachers Visit Our Archives Ask A Question How To Ask A Question Question of the Week Our Expert Scientists Volunteer at NEWTON! Frequently Asked Questions Referencing NEWTON About NEWTON About Ask A Scientist Education At Argonne Tatum's and Beadle's Theory
Name: Heather F.
Status: Student
Age: 16
Location: N/A
Country: N/A
Date: N/A 


Question:
Does the statement (featured in my biology book titled BIOLOGY 5TH EDITION by CAMPBELL, MITCHELL AND REECE), "Moreover a number of genes are known to give rise to two or more different proteins, depending on which segments are treated as exons during RNA processing," contradict that of Tatum's and Beadle's ONE GENE - ONE PROTEIN theory/hypothesis?



Replies:
No, it is the definition of a gene you are having problem with. A gene is a sequence and if two genes have overlapping sequences it does not mean it is the same gene!

Steve Sample


In science, there are exceptions to every rule. And since Beadle and Tatum's original hypothesis, we have modified it to say "one gene, one polypeptide". Recall that not only can different exons in a single gene produce a different polypeptide, but many functional proteins are made of more than one polypeptide. An example of this is hemoglobin which is made of 2 alpha and 2 beta polypeptide chains that come together to form the single protein.

van hoeck


Because one gene does NOT always end up producing just one form of the protein.

PF



Click here to return to the Molecular Biology Archives

NEWTON is an electronic community for Science, Math, and Computer Science K-12 Educators, sponsored and operated by Argonne National Laboratory's Educational Programs, Andrew Skipor, Ph.D., Head of Educational Programs.

For assistance with NEWTON contact a System Operator (help@newton.dep.anl.gov), or at Argonne's Educational Programs

NEWTON AND ASK A SCIENTIST
Educational Programs
Building 360
9700 S. Cass Ave.
Argonne, Illinois
60439-4845, USA
Update: June 2012
Weclome To Newton

Argonne National Laboratory