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Name: Aleksandra
Status: Student
Age: 20s
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Question:
Why do drugs that affect bacterial ribosomes not also affect host cell ribosomes



Replies:
Bacterial ribosomes are structurally different from eukaryotic (host cell) ribosomes. For instance, bacterial ribosomes have two ribosomal RNA molecules, whereas eukaryotes have three (5S rRNA is missing in bacteria). There are also sufficient RNA sequence differences that allow drugs to act specifically.

Trudy Wassenaar



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