What is Statistically Significant? ```Name: armin Brott Status: N/A Age: 13 Location: N/A Country: N/A Date: N/A ``` Question: I have spent the last 4 and a half hours searching the internet for an artical that uses the term "statistically significant." I need it for my science class so I can write a paragraph describing how the test was used. Replies: Great question. Here is an example which can clarify its meaning. Assume you have come up with a new drug to treat cancer. After some investigation in the lab, you are ready to try it on say, rats, and see if it works for them. Say, you find 100 sick rats and give them the medicine and 20 of them get well. OK, the question is this: does this drug work? You'd say, sure it does, it cured 20 rats. Someone else will say: no, not necessarily because 20 out of 100 rats would overcome their illness even if left alone. You'd say, OK, lets try a new method. We take 200 randomly selected sick rats. We divide them randomly into two groups of 100. We tread one of the groups with real drug and the other half with a fake pills. The person giving them the drug and taking care of them will not know which pills are real and which fake. At the end of the experiment, you count the number of rats surviving. If you see that of the group getting the real drug 20 survived and of those getting fake medicine 5 survived, then you'd say that a "statistically significant" number of rats benefited from your drug. If, on the other hand, 18 of those rats that received fake drug also survived, then you have a problem: You do not really know for sure if your drug has had any effect, because the difference between survival rates (20 vs. 18) is not "statistically significant". It can be just normal variations of some sort. As you can imagine, "statistically significant" is a very important concept and is used anytime you like to know if "on average" something works or does not work. It works if the results is statistically (that is, on average, everything else considered) significant. Good luck. Dr. Ali Khounsary Advanced Photon Source Argonne National Laboratory Click here to return to the Mathematics Archives

NEWTON is an electronic community for Science, Math, and Computer Science K-12 Educators, sponsored and operated by Argonne National Laboratory's Educational Programs, Andrew Skipor, Ph.D., Head of Educational Programs.

For assistance with NEWTON contact a System Operator (help@newton.dep.anl.gov), or at Argonne's Educational Programs