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Name: trevor ratcliff
Status: N/A
Age: N/A
Location: N/A
Country: N/A
Date: 1999 


Question:
I am interested in extracting salicin from willow bark and preparing aspirin from the extract. I am looking for any "recipes" for the procedure. Please help me if you can.



Replies:
An interesting project!

I suggest boiling the bark in plain old hot water, i.e., making tea. Then one needs to isolate the aspirin... I'm no organic chemist but I'd reduce the volume by evaporation, then put it into a sep funnel with a relatively safe organic solvent, and try to isolate the acetic acid by crystallization/recrystallization. There are probably optimal solvent choices as well as steps to take in oprder to remove unwanted impurities... all this is guesswork.

I hope this helped somewhat.

Try finding an organic chemistry laboratory manual and see if you can find experiments in which this or similar extractions are carried out.

Good luck
prof topper



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